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Status:
Approved (2333) Withdrawn (106) NDA Filing (153) Phase Ⅲ (817) Phase Ⅱ (2919) Phase Ⅰ (2275) IND Filing (61)
Clinical Stage:
Pending (1056) Active (2280) Discontinued (2850)
Company:
Unknown (1307) Pfizer (517) GlaxoSmithKline (330) Merck Sharp & Dohme (309) Sanofi (299) Novartis (239) Roche (231) AstraZeneca (228) Bristol-Myers Squibb (174) Lilly (157) Astellas (153) Takeda (117) Bayer (113) Daiichi Sankyo (102) Abbvie (98) Johnson & Johnson (98) National Cancer Institute (87) Boehringer Ingelheim (84) Mitsubishi Tanabe Pharma (84) Gilead (69) Eisai (68) Abbott (64) Teva (62) Janssen (57) Allergan (55) Otsuka (52) Sumitomo Dainippon (49) Merck Serono (48) Shionogi (48) Shire (48) Ono Pharmaceutical (46) Amgen (45) Celgene (41) Vertex (40) Valeant (38) Ligand (35) Kyowa Hakko Kirin (33) UCB (30) Lundbeck (29) Chugai (28) Novo Nordisk (28) Pierre Fabre Pharmaceutical (28) Servier (28) Taiho Pharma (28) Actelion (27) Jiangsu Hengrui Medicine (27) Ionis Pharmaceuticals (26) Japan Tobacco (25) Taisho Pharmaceutical (25) Leo Pharma (24) Shanghai Institute of Materia Medica, Chinese Academy of Sciences (24) Hansoh Pharma (22) Meiji Seika Pharma (22) Almirall (21) Orion (21) Exelixis (20) Genzyme (20) Incyte (20) Theravance Biopharma (20) Ferring Pharmaceuticals (19) Genentech (19) Ipsen (19) Nippon Shinyaku Pharma (19) Vernalis (19) Baxter (18) Santen (18) Array BioPharma (17) Endo (17) Kissei (17) Kowa (17) Teijin Pharma (17) Esteve Pharmaceutical (16) Kyorin (16) NeuroSearch (16) Alcon (15) Forest (15) Gedeon Richter (15) Millennium Pharmaceutical (15) National Institutes of Health (15) SK biopharmaceuticals (15) Chiesi (14) Institute of Materia Medica Chinese Academy of Medical Sciences (14) Lee's Pharm (14) vTv Therapeutics (14) BTG plc (13) Biogen (13) Chong Kun Dang (13) Meda Pharmaceuticals (13) Nicox (13) Purdue Pharma (13) Recordati (13) ViiV Healthcare (13) Dong-A Pharmaceutical (12) Medivir (12) Zydus cadila (12) LG Life Sciences (11) Maruho Pharmaceutical (11) MedImmune (11) Spectrum Pharmaceuticals (11) Zeria (11) 未知 (0)
Indication:
Squamous cell cancer (1) Meningitis (2) Non-alcoholic steatohepatitis (10) Acid-related diseases (3) Acne (48) Actinic keratosis (AK) (19) Acute bacterial exacerbation of chronic obstructive pulmonary disease (1) Acute bacterial skin and skin structure infections (ABSSSI) (16) Acute coronary syndrome (ACS) (25) Acute cystitis (3) Acute exacerbation of chronic bronchitis (AECB) (2) Acute liver damage caused by drug (1) Acute lymphoblastic leukaemia (ALL) (31) Acute myeloid Leukemia (AML) (101) Acute otitis media (3) Acute otitis externa (AOE) (2) Acute promyelocytic leukemia (APL) (3) Acute pyelonephritis (AP) (2) Acute rejection in renal transplantation (1) Acute respiratory failure (2) Acutely decompensated congestive heart failure (ADHF) (1) Addictive disorders (2) Adjunct treatment for epilepsy (1) Adjuncts to anesthesia (2) Advanced breast cancer (3) Advanced non-squamous non small cell lung cancer (NSCLC) (1) Advanced or metastatic breast cancer (2) Advanced ovarian cancer (3) Advanced prostate cancer (5) Advanced renal cell carcinoma (RCC) (8) AIDS-related Kaposi’s sarcoma (2) Alcohol dependence (13) Allergic conjunctivitis (28) Allergic rhinitis (AR) (79) Allergic rhinoconjunctivitis (1) Alzheimer's disease (AD) (214) Amyotrophic lateral sclerosis (ALS) (21) Anaesthetic (23) Anemia (29) Angina pectoris (82) Anxiety (140) Appendicitis (1) Arrhythmia (94) Tachyarrhythmia (3) Arthritis (32) Aspergillosis (4) Asthma (274) Atherosclerosis (48) Atopic dermatitis (59) Atrial fibrillation (30) Atrial flutter (6) Attention deficit hyperactivity disorder (ADHD) (39) Basal cell carcinoma (BCC) (6) BCG-refractory carcinoma in situ of the urinary bladder (1) Benign prostatic hypertrophy (46) Bipolar I disorder (6) Bipolar mania (4) Bladder cancer (24) Bone marrow cancer (1) BRAF mutant melanoma (3) Brain ischemia (4) Thyrotoxicosis (5) BRCA-deficient breast cancer (1) Non-diabetic renal diseases (1) Mercury poisoning (1) lead poisoning (3) Breast cancer (178) Vitiligo (4) Bronchial asthma (15) Bronchiectasis (5) delayed puberty (1) Varicose veins (5) Cancer chemotherapy (14) Nasal Congestion (16) Cancer related cachexia (6) Cancer related pain (11) Poisoning (13) promote weight gain after weight loss following extensive surgery (1) Candidiasis (22) Hypothyroidism (3) Carcinoid syndrome (2) Cardiovascular risk reduction (2) Phaeochromocytoma (3) Castration-resistant prostate cancer (CRPC) (1) Hyperkalaemia (7) Inflammation after cataract surgery (1) Herpes zoster (7) Cerebral infarction (6) Precocious puberty in children (2) Carnitine deficiency (1) Cerebral vasospasm (4) Conjunctivitis (10) Keratitis (3) Cerebrovascular diseases (21) Blepharitis (2) Chemotherapy-induced nausea and vomiting (16) Chemotherapy-induced peripheral neuropathy (3) Airways obstruction (2) Leprosy (3) Oedema (21) Chronic angina (3) Chronic back pain (2) Methaemoglobinaemia (1) Apnoea (1) Thyrotrophic adenoma (1) Mydriasis (2) Chronic bronchitis (4) Cycloplegia (3) Chronic constipation (3) Chronic gout (5) Chronic idiopathic constipation (CIC) (8) Chronic idiopathic urticaria (CIU) (6) Anorexia (2) Chronic immune thrombocytopenia (2) Chronic iron overload (2) Chronic lymphocytic leukemia (CLL) (54) Excessive bleeding (1) Chronic myeloid leukemia (CML ) (30) Chronic neuropathic pain (3) Episcleritis (2) Chronic obstructive pulmonary disease (COPD) (148) Miosis (1) Chronic pain (11) Fever (17) Rubefaction (2) ischaemic heart disorder (34) Chronic thromboembolic pulmonary hypertension (CTEPH) (1) Soft tissue disorders (5) Chronic urticaria (3) Menorrhagia (3) Chronic viral hepatitis (1) Clostridium difficile infection (7) Clostridium difficile-associated diarrhea (CDAD) (3) Pigmented villonodular synovitis (1) Cutaneous larva migrans (1) Dracunculiasis (1) Vitamin B12 deficiency (3) Cytomegalovirus (CMV) retinitis (3) Coccidioidomycosis (1) Congenital heart disease (1) Cognitive disorders (62) Cold sore infections (1) Colorectal disorder (2) Colorectal neoplasms (5) Disorder caused by hyperprolactinemia (2) Orthostatic hypotension (3) Circulation disturbance (2) Community-acquired bacterial pneumonia (CABP) (1) Giardia lamblia disease (7) Onchocerciasis (4) Community-acquired pneumonia (CAP) (21) Schistosomiasis (3) Hepatic fascioliasis (1) Lymphatic filariasis (2) Complicated intra-abdominal infection (3) Toxocariasis (2) Worm infection (5) Complicated urinary tract infection (3) Hookworm infections (3) Ascaris infection (5) Congestive heart failure (9) Conscious sedation (1) Acute iron poisoning (1) Stimulant (2) Constipation (18) Thrombotic microangiopathy (1) Contrast agents (21) Menopausal symptoms (9) Menopausal hormone replacement therapy (15) Trichostrongyliasis (1) Coronary artery disease (CAD) (19) Chronic hepatitis (4) Musculoskeletal and joint disorders (9) Prostate disorders (1) Crohn's disease (26) Vaginal trichomoniasis (3) Cryptococcus neoformans (4) Bradycardia (2) Asystole (1) Cushing's disease (9) Headache (4) Delayed graft function (4) Cutaneous fungal infections (9) Cutaneous T cell lymphoma (CTCL) (12) Respiratory-tract disorders (10) Cystic fibrosis (CF) (34) Peripheral vascular disorders (20) Cytoprotective adjuvant (2) Iron-deficiency anemia (8) Anaplastic lymphoma kinase (ALK)-positive NSCLC (2) ROS1-positive non-small cell lung cancer(NSCLC) (1) Gastrointestinal haemorrhage (1) Deep vein thrombosis (DVT) (11) Homocystinuria (1) Cholera (2) Lyme disease (3) Delayed sleep onset (1) Rheumatic fever (1) Adrenocortical insufficiency (6) Vintamin B1 deficiency (5) Postpartum or postabortal haemorrhage (1) Hyperprolactinaemia (2) Dementia (18) Vitamin B2 deficiency (2) Vitamin K deficiency (1) Hypoprothrombinemia (2) Depression (107) Diabetic dyslipidemia (2) Gastrointestinal infections (1) Amoebiasis (12) Bronchitis (6) Trichomoniasis (5) Diabetic macular edema (17) Seborrhoea (1) Trichuriasis (1) Diabetic nephropathy (45) American trypanosomiasis (2) Diabetic neuropathic pain (DNP) (9) Herpes simplex virus (11) Diarrhea (17) Visceral spasms (12) Spinocerebellar degeneration (1) Irritable bowel syndrome with diarrhea (IBS-D) (5) Differentiated thyroid cancer (3) Digestive system diseases (2) Dravet syndrome (2) Infections of the eye (8) Susceptible protozoal infections (2) Dry age related macular degeneration (AMD) (3) Chronic pancreatitis (1) Dry eye disease (14) Hepatic disorders (11) Hepatic encephalopathy (4) Dry mouth (2) Pituitary gigantism (1) Duchenne muscular dystrophy (DMD) (21) Duodenal ulcer (21) Uveal melanoma (3) Dysbetalipoproteinemia (1) Dyslipidemia (38) Dysmenorrhea (15) Dyspareunia-pain during sex (2) Dyspepsia (10) Dysuria (2) Gynaecological disorders (3) Eczema (11) Emergency contraception (3) Suppress the secretion of thyroid-stimulating hormone (1) Nephrotic syndrome associated with primary glomerular disease (1) Emphysema (4) Irritability associated with pediatric autism spectrum disorder (1) Anorectal disorders (1) Endometrial cancer (14) Choleresis (7) Rheumatic disorders (30) Endometriosis (30) Psychedelic (1) Transplant rejection (12) Capillary impairment (1) Epidermolysis bullosa (1) Common warts (6) Epilepsy/Seizures (89) Sunburn (1) ER positive metastatic breast cancer (1) Cold (5) Zinc supplement (2) Erectile dysfunction (ED) (40) wound (3) Erosion and ulceration (2) Magnesium sulfate overdose (1) Hydrofluoric acid burns (1) Hypocalcaemia (2) Erosive esophagitis (EE) (5) Eye disorders (9) Erythema nodosum leprosum (ENL) (2) Essential hypertension-重复 (9) Renal calculi (1) Essential thrombocythaemia (ET) (3) Asphyxia (1) Biliary-tract disorders (4) Excessive sleepiness (3) Vitamin B6 deficiency (2) Exercise-induced bronchoconstriction (EIB) (1) Analgesia induction and maintenance (1) Vitamin D deficiency (2) Facial acne vulgaris (3) Female sexual dysfunction (8) Fibromyalgia (FM) (14) Follicular B cell non-Hodgkin lymphoma (FL) (1) Follicular lymphoma (6) Fragile X syndrome (5) Friedreich's ataxia (4) Functional dyspepsia (3) Gastric cancer (42) Gastric ulcer (31) Gastroesophageal reflux disease (GERD) (41) Gastrointestinal stromal tumors (GISTs) (14) Gaucher's disease (GD) (4) Generalised anxiety disorder (GAD) (19) Generalized tonic-clonic status epilepticus (GTCSE) (2) Germline BRCA mutated advanced ovarian cancer (2) Digital ulcers (1) Cataract (3) Pancreatitis (6) Glaucoma (56) Glioblastoma multiforme (19) Gonorrhea (10) Induced mydriasis (1) Gout and hyperuricemia 删去 (2) Essential hypotension (1) Opioid central depression (1) Gram-positive and Gram-negative bacterial infections (15) Retinal disorders (2) Wet age-related macular degeneration (2) Growth hormone deficit (5) Cytomegalovirus infections (11) HBV infection (54) Dyskinesia (4) HCV infection (140) Head lice infestation (4) Behavioural disorders (6) Heart failure (19) Heart failure (127) Endocrine disorders (2) Hematopoietic stem cell transplantation (HSCT) (4) Hyperthyroidism crisis (1) Hepatocellular carcinoma (HCC) (45) Peritonitis (3) Septicaemia (5) Heart disease (4) Gallbladder disorders (1) Hereditary tyrosinemia (1) Biliary spasticity (1) Retinoblastoma (1) Herpes zoster keratitis (4) Adult respiratory distress syndrome (ADRS) (1) Decrease appetite (1) HIV infection (192) Hormone receptor positive early breast cancer (1) Hormone refractory prostate cancer (2) HSV infection (6) Huntington's disease (16) Hyperammonaemia (7) Cystinuria (3) Hyperbilirubinemia (1) Hypercalcemia (14) Hypercholesterolemia (46) Hyperlipidemia (80) Hyperparathyroidism (8) Hypertension (296) Hypertriglyceridemia (15) Hyperuricemia (12) Hypogonadotropic hypogonadism (3) Hyponatremia (5) Euvolemic hyponatremia (1) Idiopathic pulmonary fibrosis (IPF) (17) Idiopathic thrombocytopenic purpura (ITP) (4) Ileus (2) Immunostimulant (1) Immunosuppressant (2) Ischaemia (3) Impetigo (4) Fissure in ano (1) Dystonia (1) Inflammatory bowel disease (32) Influenza virus infection (13) Insomnia (75) Invasive aspergillosis (5) Somatotropin deficiency (2) Invasive mucormycosis (1) Irritable bowel syndrome (IBS) (37) Irritable bowel syndrome with constipation (IBS-C) (5) Juvenile rheumatoid arthritis (JRA) (6) Keratinocytes type scabies (1) Lambert-Eaton myasthenic syndrome (LEMS) (2) Leigh syndrome (1) Leiomyoma (4) Thromboangiitis obliterans (2) Lesch-Nyhan Disease (1) Leukemia (41) Pseudomonal infection (1) Localized submental fat (1) Lung cancer (40) Lymphoma (80) Macular degeneration (2) Major depressive disorder (MDD) (116) Malignancies (65) Malignant brain tumor (3) Mania (8) Mantle cell lymphoma (MCL) (13) Medullary thyroid cancer (MTC) (3) Renal osteodystrophy (1) Medulloblastoma (1) Aplastic anaemia (2) Melanoma (58) Metastatic breast cancer (16) Metastatic prostate carcinoma (6) Metastatic castration-resistant prostate cancer (mCRPC) (5) Metastatic colorectal cancer (CRC) (5) Metastatic gastric carcinoma (2) Metastatic melanoma (8) Methanol poisoning (1) Haematological disorders (1) Migraine (66) Mixed dyslipidemia (3) Chemotherapy-induced anaemia (1) Moderate-to-severe acute pain (2) Monitored anesthesia care (MAC) (1) Mood disorder (4) Motion sickness (4) Multiple folliculitis (1) Multiple myeloma (MM) (68) Multiple sclerosis (MS) (53) Muscle relaxant (6) Myelodysplastic syndrome (MDS) (38) Myelofibrosis (10) Myeloid leukemia (4) Leucopenia (1) Myocardial infarction (MI) (51) Vascular disorders (3) Myocardial perfusion imaging (MPI) (1) Nail scabies (4) Narcolepsy (11) Nausea and vomiting (42) Systemic amyloidosis (1) Neuropathic pain (68) Erythropoietic protoporphyria (1) Niemann-Pick diseases (4) Non small cell lung cancer (NSCLC) (179) Haemolytic uraemic syndrome (1) Non-24-hour sleep-wake disorder (N24HSWD) (1) Non-alcoholic fatty liver disease (NAFLD) (21) Non-Hodgkin B-cell lymphomas (9) Non-Hodgkin’s lymphoma (NHL) (44) Non-small cell lung cancer associated anorexia or cachexia (1) Non-ST elevation acute coronary syndrome (NSTE-ACS) (2) NSAID-associated gastric ulcer (2) Obesity (111) Fatty liver (1) Ocular histoplasmosis (1) Ocular hypertension (40) Onychomycosis (5) Open-angle glaucoma (20) Ophthalmologic surgical procedures (2) Opioid induced constipation (OIC) (6) Osteoarthritis (OA) (82) chronic low back pain (1) Osteogenesis imperfecta (1) Osteomalacia (2) Lung disorders (1) Osteoporosis (32) Osteosarcoma (3) Nephritis (3) Ovarian cancer (92) Overactive bladder (OAB) (40) Ovulation induction (1) Paget's disease (10) Pancreatic cancer (81) Neuroprotection (4) Parkinson's disease (PD) (111) Partial seizures (13) Pathologic myopia (1) Pelvic inflammatory disease (4) Peptic ulcer (79) Percutaneous coronary intervention (PCI) (6) Bone disorders (1) Percutaneous transluminal coronary angioplasty (PTCA) (1) Perennial allergic rhinitis (6) Periodontitis (3) Angioedema (2) Peripheral arterial disease (PAD) (13) Peripheral T cell lymphoma (PTCL) (7) Peripheral  neuropathy (1) Plasmodium vivax malaria (2) Lipid metabolism disorders (4) Pleural mesothelioma (5) Pneumonia (13) Post-essential thrombocythemia (1) Postherpetic neuralgia (PHN) (22) Postmenopausal osteoporosis (29) Postmyocardial Infarction Syndrome (1) Postoperative nausea and vomiting (6) Postoperative pain (32) Viral infections (6) Post-polycythemia vera (2) Prader-Willi syndrome (6) Premature ejaculation (6) Premature LH surges (3) Prevention of preterm labor (5) Thrombosis (5) Glutamine deficiency (1) Primary biliary cirrhosis (PBC) (6) Primary hypercholesterolemia (5) Kidney disorders (3) Primary hypertension (5) Primary hypogonadism (3) Prostate cancer (131) Psoriasis (89) Psoriatic arthritis (4) Pulmonary arterial hypertension (31) Pulmonary embolism (7) Reflux esophagitis (5) Rejection of organ transplantation (6) Renal cell carcinoma (25) Respiratory tract infection (25) Restless legs syndrome (10) Rheumatoid arthritis (RA) (206) Rickets (3) Lactose intolerance (1) Varicella zoster virus infections (1) Schizophrenia (164) Dermal scarring (4) Subarachnoid haemorrhage (2) Seasonal allergic rhinitis (17) Corneal epithelial defects (1) Secondary amyloid A amyloidosis (1) Secondary hyperparathyroidism (HPT) (10) Sedation (21) Lennox-Gastaut syndrome (LGS) (3) Sensitive anaerobic bacteria infections (5) Sinus tachycardia (1) Sinusitis-重复 (1) Sjoegren's syndrome (6) Skin infectious (26) Sleep disorder (17) Sleep initiation and maintenance disorders (1) Small cell lung cancer (SCLC) (37) Small lymphocytic lymphoma (SLL) (2) Smoking cessation (10) Social withdrawal (4) Male infertility (2) Soft tissue infections (10) Soft tissue sarcoma (10) Solid tumours (644) Spasticity due to multiple sclerosis (1) Stable plaque psoriasis (3) Back pain (2) Stroke and systemic embolism (3) Superficial basal cell carcinoma (sBCC) (1) Superficial infection of the skin (1) Superficial punctate keratitis (1) Systemic lupus erythematosus (21) Tardive dyskinesia (4) T-cell acute lymphoblastic leukemia (T-ALL) (2) Marburg virus disease (2) Thrombocytopenia (11) Thrombotic cardiovascular events (TCE) (5) Thyroid cancer (4) Metabolic disorders (3) Tinnitus (7) Tissue regeneration in diabetic ulcers and scars (1) Tonsillitis (1) Topical bacterial infection (2) Heart arrest (2) Tourette's syndrome (6) Transthyretin familial amyloid polyneuropathy (TTR-FAP) (1) Triple negative breast cancer (3) Exanthema (1) Tuberculosis (29) Type 2 diabetes (301) Ulcerative colitis (41) Urea cycle disorders (UCDs) (2) Uremic pruritus (2) Urinary frequency (11) Urinary incontinence (34) Urinary tract infections (33) Urinary urgency (5) Streptococcal infection (1) Urticaria (25) Uterine fibroids (10) Uveitis (6) Malignant pleural effusion (1) Vaginitis (12) Rhabdomyosarcoma (1) Neurogenic detrusor overactivity (1) Venous thromboembolism (VTE) (13) Ventilator-associated pneumonia (1) Vulvovaginal atrophy (2) Zollinger-Ellison syndrome (7) Surgical blood loss (1) Erythema (1) Glomerulonephritis (3) Reperfusion injury (3) Central nervous systeml trauma (1) Head and neck cancer (35) Veno-occlusive disorders (1) Bone cancer (1) Nasopharyngeal cancer (3) Genital warts (2) Intervertebral disc displacement (1) Amyloid polyneuropathy (1) Cervical intraepithelial neoplasia (1) Influenza A virus infections (3) Glycogen storage disease type I (2) Lupus vulgaris (1) Polycythaemia vera (1) Fabry disease (3) Leg ulcer (3) Hodgkin lymphoma (13) Cardiac ischemic complications (2) Colorectal cancer (73) Respiratory depression (8) Prophylaxis of organ rejection (2) Rejection of renal transplantation (7) Rejection of liver transplantation (2) Rejection of lung transplantation (1) Mycoses (6) Herpes labialis (4) Genital herpes (2) Diabetic complications (3) Myocardial reperfusion injury (1) Rejection of pancreatic transplantation (1) Anastomotic ulcer (1) Cardiogenic shock (1) Primary peritoneal cancer (2) Fallopian tube cancer (5) Picornavirus infections (1) Epithelial ovarian cancer (3) Renal parenchymal hypertension (1) neurodermatitis (1) Ventricular arrhythmias (3) Bone metastases pain (1) Diabetes insipidus (1) Uterine leiomyoma (3) Ankylosing Spondylitis (AS) (10) Primary dysmenorrhea (PD) (2) Familial adenomatous polyposis (FAP) (3) Iritis (2) Cyclitis (1) Life- or limb-threatening infections caused by susceptible strains (2) Rosacea (2) Helicobacter pylori infection (1) Venous insufficiency (1) Acute pain (AP) (8) Bacteraemia (1) Low back pain (4) Shoulder periarthritis (1) Tendonitis (1) Hypoxia (1) Cervico-omo-brachial syndrome (1) Pulmonary arterial hypertension secondary to scleroderma (2) IgA nephropathy (1) After surgery, post-traumatic and anti-inflammatory (1) Wound infections (1) Nosocomial infections (1) Male sexual dysfunction (1) Peroxisomal disorders (PD) (1) Varicose ulcer (1) Tropical spastic paraparesis (1) Inborn errors in primary bile acid synthesis (1) Andropause (1) Prevention of atherothrombotic events (2) Tinea corporis (1) Tinea cruris (1) Pediculosis (1) Tinea pedis (4) Fungal infection (42) Helicobacter infections (1) Postoperative inflammation and pain following ocular surgery (2) Nephropathic cystinosis (1) Urinary retention (1) Diabetic angiopathies (1) Candidemia (2) Abscesses (1) Oesophageal varices (3) Bronchospasm (1) Nosocomial Pneumonia (NP) (5) Osteoporosis in men (2) Glucocorticoid-induced osteoporosis (1) Maintenance dialysis (1) Pulmonary sarcoidosis (1) Ethylene glycol poisoning (1) Gastritis (13) Marginal zone lymphoma (1) Chronic gouty arthritis (1) Chronic respiratory diseases (2) Intermittent gouty arthritis (1) Gastrointestinal disorders (3) Surgical infection (2) Relapsing fever (1) Louse-borne typhus (1) Gingivitis (1) Superficial bladder cancer (1) Recurrent mucocutaneous herpes infection (1) Pneumocystis pneumonia (3) Tinea capitis (1) Meningococcal infection (1) Neonatal respiratory distress syndrome (2) Hypertensive crisis (1) Vaginal candidiasis (2) Neonatal gonococcal eye infection (1) Bulimia nervosa (1) Dermatophyte infections (3) Perianal warts (1) Urethral meatus warts (1) Hyperlipoproteinaemia type IIa (2) Monosymptomatic hypochondria (1) Paranoid psychoses (1) Chorea (1) Taste disorders (1) Gastric varices (1) Solar lentigines (1) Superficial candidiasis (1) Extrapulmonary tuberculosis (2) Gestational trophoblastic disease (1) Myeloproliferative Disorders (MPD) (6) Nonseminomatous testicular cancer (1) Endocarditis (1) Enterobiasis (1) Babesiosis (1) Dysfunctional uterine bleeding (1) Malignant hyperthermia (1) Convulsions (1) Cryptosporidiosis (2) Supraventricular arrhythmias (1) Familial hypophosphatemia (1) Colitis (1) Black widow spider bites (1) Acute ulcerative gingivitis (1) Megaloblastic anaemia (1) Recurrent epithelial keratitis (1) Primary keratoconjunctivitis (1) Wilms Tumor (1) Testicular cancer (1) Aggressive systemic mastocytosis (ASM) (2) 流产 (1) Hypereosinophilic syndrome (HES) (2) Dermatofibrosarcoma protuberans (DFSP) (1) Chronic eosinophilic leukemia (CEL) (1) Chronic kidney disease (8) Systemic bacterial infections (13) Colon cancer (9) Transient ischaemic attacks (1) Muscle hypertonia (4) Complicated skin and skin structure infections (cSSSI) (5) Hives (2) Cirrhosis (4) Dermatitis (20) Cystitis (1) Prurigo (2) Hepatitis (1) Skin pruritus (23) Spinal stenosis (1) Catheter infections (1) Autosomal dominant polycystic kidney disease (ADPKD) (2) Advanced or metastatic transitional cell carcinoma (1) Acute enterocolitis (1) Dystocia (1) Suicidal ideation (1) Transfusion-related iron overload (2) microsporidiosis (1) Diabetic foot ulcers (8) Nyctalopia (1) Susceptible bacterial infections (45) Paroxysmal Nocturnal Hemoglobinuria (PNH) (1) Systemic mastocytosis with associated hematological neoplasm (1) Mast cell leukemia (1) Chronic heart failure (2) Chronic heart failure (8) Acute angina (1) Malignant Ascites (1) Familial hypercholesterolemia (7) Anthrax (3) Neuroblastoma (8) Heterozygous familial hypercholesterolemia (2) Staphylococcus aureus bloodstream infections (3) T-cell 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