RS-130830

CTS-1027 had been in phase II clinical trials by Conatus Pharmaceuticals (licensed from Roche) for the treatment of HCV infection. However, this study was discontinued due to abnormalities and adverse events in a subset of clinical trial participants. This compound was originally discovered by Roche for the treatment of Arthritis, but there is no development report for this study.

General Information

Update Date:2015-10-14

Drug Name:
RS-130830
Research Code:
RS-130830; CTS-1027; RO-1130830
Trade Name:
MOA:
Matrix metalloprotease (MMP) inhibitor
Indication:
HCV infection; Arthritis
Status:
Phase II (Discontinued)
Company:
Roche (Originator) , Conatus
Sales:
ATC Code:
Chemical Structure

Update Date:2015-10-14

Molecular Weight 425.88
Formula C19H20ClNO6S
CAS No. 193022-04-7 (RS 130830);
Chemical Name 2H-Pyran-4-carboxamide, 4-[[[4-(4-chlorophenoxy)phenyl]sulfonyl]methyl]tetrahydro-N-hydroxy-
RS 130830 (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
425.88 2 7 7 110 2.977±0.479
*:Calculated by ACD/Labs software V11.02.