Istaroxime

Istaroxime is in phase II clinical trials for the treatment of heart failure by CVie Therapeutics (A division of Lee's Pharmaceutical).

The compound was originally discovered by Sigma-Tau, then CVie Therapeutics acquired the rights of the drug.

General Information

Update Date:2015-10-14

Drug Name:
Istaroxime
Research Code:
Debio-0614; PST-2744; ST-2744
Trade Name:
MOA:
Na+/K+-ATPase inhibitor
Indication:
Heart failure
Status:
Phase II (Active)
Company:
Sigma-Tau  (Originator) , Lee's pharmaceuticals
Sales:
ATC Code:
Chemical Structure

Update Date:2015-10-14

Molecular Weight 360.49
Formula C21H32N2O3
CAS No. 203737-93-3 (Istaroxime);
Chemical Name Androstane-3,6,17-trione, 3-[O-(2-aminoethyl)oxime], (5a)-
Istaroxime (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
360.49 2 5 4 81.8 2.288±0.459
*:Calculated by ACD/Labs software V11.02.