Bufuralol

Bufuralol has been in phase III clinical trials for the treatment of hypertension. However, this research has been discontinued.

The compound was co-developed by Roche and Helsinn.

General Information

Update Date:2016-05-26

Drug Name:
Bufuralol
Research Code:
Bufuralol; Ro-34787
Trade Name:
MOA:
β-adrenoceptor antagonist
Indication:
Hypertension
Status:
Phase Ⅲ (Discontinued)
Company:
Roche (Originator), Helsinn (Originator)
Sales:
ATC Code:
Chemical Structure

Update Date:2015-11-11

Molecular Weight 261.36
Formula C16H23NO2
CAS No. 54340-62-4 (Bufuralol);
Chemical Name 2-Benzofuranmethanol, a-[[(1,1-dimethylethyl)amino]methyl]-7-ethyl-
Bufuralol (Free Acid/Base)Parameters:
MW HD HA FRB* PSA* cLogP*
261.36 2 3 6 45.4 3.538±0.362
*:Calculated by ACD/Labs software V11.02.
Synthesis & Impurities

Update Date:2016-02-24


Impurity database is being updated!